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.dropdown-item:focus-visible{background:#f6f8fb!important;color:#0d47a1!important}.app-navbar__search[data-v-0504dad4]{min-width:min(24rem,34vw)}.navbar-search-item[data-v-0504dad4]{margin:0}.app-navbar__account[data-v-0504dad4]{align-items:center}.app-navbar__login[data-v-0504dad4] .nav-link{border:1px solid #cfd8e3;background:#fff}[data-v-0504dad4] .navbar-toggler{width:40px;height:40px;padding:.45rem;border:1px solid #cfd8e3;border-radius:8px;background:#fff}[data-v-0504dad4] .navbar-toggler:focus{box-shadow:0 0 0 .2rem #0d47a129;outline:none}[data-v-0504dad4] .navbar-toggler:hover{border-color:#9fb3c8;background-color:#f6f8fb}[data-v-0504dad4] .navbar-toggler-icon{width:1.25em;height:1.25em;background-image:url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='%23344054' stroke-linecap='round' stroke-miterlimit='10' stroke-width='2.25' d='M4 7h22M4 15h22M4 23h22'/%3e%3c/svg%3e")}@media(max-width:991.98px){.app-navbar__bar[data-v-0504dad4]{padding-right:.75rem;padding-left:.75rem}[data-v-0504dad4] .navbar-collapse{position:absolute;top:calc(100% + .35rem);right:.75rem;left:.75rem;z-index:1050;padding:.55rem;border:1px solid #d9e1ec;border-radius:8px;background:#fff;box-shadow:0 16px 40px #10182824}.app-navbar__menus[data-v-0504dad4],.app-navbar__account[data-v-0504dad4],.app-navbar__mobile-search[data-v-0504dad4]{gap:.25rem;align-items:stretch}[data-v-0504dad4] .nav-link{justify-content:flex-start;width:100%;border-radius:6px}.app-navbar__mobile-search[data-v-0504dad4]{margin-top:.35rem}}@media(max-width:420px){.brand-container--compact[data-v-0504dad4]{gap:.45rem}.app-logo[data-v-0504dad4]{width:40px;height:40px}.app-name[data-v-0504dad4]{font-size:1rem}.version-display[data-v-0504dad4]{font-size:.62rem}}@media(prefers-reduced-motion:reduce){.app-logo[data-v-0504dad4],[data-v-0504dad4] .nav-link{transition:none}.app-logo[data-v-0504dad4]:hover,[data-v-0504dad4] .nav-link:hover{transform:none}}.app-footer__bar[data-v-362a77b6]{min-height:48px;padding:.25rem 1rem;border-top:1px solid #d9e1ec;background:#fffffff5;box-shadow:0 -10px 28px #1e293b14;-webkit-backdrop-filter:blur(12px);backdrop-filter:blur(12px)}.bg-footer[data-v-362a77b6]{background-image:none}.footer-shell[data-v-362a77b6]{display:flex;flex:0 0 auto;align-items:center;justify-content:space-between;min-width:9rem}.footer-links[data-v-362a77b6],.footer-partners[data-v-362a77b6]{display:flex;align-items:center}.footer-partners[data-v-362a77b6]{flex:1 1 auto;justify-content:flex-end;gap:.35rem}.app-footer__collapse[data-v-362a77b6]{flex:1 1 auto}.disclaimer-indicator[data-v-362a77b6]{gap:.25rem;flex-shrink:0}.disclaimer-indicator__btn[data-v-362a77b6]{display:inline-flex;align-items:center;justify-content:center;gap:.35rem;min-height:32px;padding:.25rem .55rem;border:1px solid #cfd8e3;border-radius:999px;background:#fff;color:#0d47a1;font-size:.8rem;font-weight:700;cursor:pointer;transition:background-color .15s ease,border-color .15s ease,transform .15s ease}.disclaimer-indicator__btn[data-v-362a77b6]:hover{border-color:#9fb3c8;background:#eef4ff;transform:translateY(-1px)}.disclaimer-indicator__btn[data-v-362a77b6]:focus-visible{outline:2px solid #0d47a1;outline-offset:2px}.disclaimer-indicator__check[data-v-362a77b6]{color:#2e7d32;font-size:.8rem;line-height:1}[data-v-362a77b6] .footer-link .nav-link{display:inline-flex;align-items:center;justify-content:center;min-width:34px;min-height:30px;padding:.12rem .38rem;border-radius:8px;transition:background-color .15s ease,transform .15s ease}[data-v-362a77b6] .footer-link .nav-link:hover,[data-v-362a77b6] .footer-link .nav-link:focus-visible{background:#f6f8fb;transform:translateY(-1px)}[data-v-362a77b6] .footer-logo{display:block;width:auto;max-width:104px;max-height:26px;object-fit:contain}[data-v-362a77b6] .footer-logo--icon{max-width:26px}[data-v-362a77b6] .footer-logo--license{max-width:86px}[data-v-362a77b6] .footer-logo--partner{max-width:96px}@media(prefers-reduced-motion:reduce){.disclaimer-indicator__btn[data-v-362a77b6],[data-v-362a77b6] .footer-link .nav-link{transition:none}.disclaimer-indicator__btn[data-v-362a77b6]:hover,[data-v-362a77b6] .footer-link .nav-link:hover,[data-v-362a77b6] .footer-link .nav-link:focus-visible{transform:none}}[data-v-362a77b6] .navbar-toggler{width:36px;height:36px;padding:.4rem;border:1px solid #cfd8e3;border-radius:8px;background:#fff}[data-v-362a77b6] .navbar-toggler:focus{box-shadow:0 0 0 .2rem #0d47a129;outline:none}[data-v-362a77b6] .navbar-toggler:hover{border-color:#9fb3c8;background-color:#f6f8fb}[data-v-362a77b6] .navbar-toggler-icon{width:1.15em;height:1.15em;background-image:url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='%23344054' stroke-linecap='round' stroke-miterlimit='10' stroke-width='2.25' d='M4 7h22M4 15h22M4 23h22'/%3e%3c/svg%3e")}@media(max-width:575.98px){.app-footer__bar[data-v-362a77b6]{padding:.25rem .75rem}.footer-shell[data-v-362a77b6]{width:100%}.app-footer__collapse[data-v-362a77b6]{margin-top:.3rem;padding-top:.3rem;border-top:1px solid #edf1f7}.footer-partners[data-v-362a77b6]{flex-wrap:wrap;justify-content:center}}.skip-link[data-v-644ba646]{position:absolute;top:-40px;left:0;background:var(--medical-blue-700, #0d47a1);color:#fff;padding:.5rem 1rem;text-decoration:none;z-index:9999;border-radius:0 0 .25rem;transition:top .15s ease-in-out;pointer-events:none}.skip-link[data-v-644ba646]:focus{top:0;pointer-events:auto;outline:3px solid white;outline-offset:-.25rem}@media(prefers-reduced-motion:reduce){.skip-link[data-v-644ba646]{transition:none}}.disclaimer-dialog[data-v-c2acd3db]{overflow:hidden}.disclaimer-header[data-v-c2acd3db]{display:flex;align-items:center;gap:.75rem;padding:1.25rem 1.5rem;background:linear-gradient(135deg,#fff3e0,#ffe0b2);border-bottom:2px solid #f57c00}.disclaimer-header__icon[data-v-c2acd3db]{font-size:1.5rem;color:#f57c00}.disclaimer-header__title[data-v-c2acd3db]{font-weight:700;color:#e65100}.disclaimer-body[data-v-c2acd3db]{padding:1.5rem;max-height:60vh;overflow-y:auto}.disclaimer-section__heading[data-v-c2acd3db]{font-weight:600;color:var(--medical-blue-700, #0d47a1);margin-bottom:.75rem;display:flex;align-items:center;gap:.5rem}.disclaimer-section__text[data-v-c2acd3db]{color:var(--neutral-800, #424242);line-height:1.6;margin-bottom:.75rem}.disclaimer-section__list[data-v-c2acd3db]{color:var(--neutral-800, #424242);line-height:1.6;padding-left:1.25rem}.disclaimer-section__list li[data-v-c2acd3db]{margin-bottom:.5rem}.disclaimer-divider[data-v-c2acd3db]{border-top:1px dashed var(--neutral-300, #e0e0e0);margin:1rem 0}.disclaimer-link[data-v-c2acd3db]{color:var(--medical-blue-700, #0d47a1);text-decoration:underline}.disclaimer-footer[data-v-c2acd3db]{display:flex;justify-content:flex-end;padding:1rem 1.5rem;border-top:1px solid var(--neutral-200, #eeeeee);background:var(--neutral-50, #fafafa)}@media(prefers-reduced-motion:reduce){.disclaimer-body[data-v-c2acd3db]{scroll-behavior:auto}}.reload-prompt[data-v-bf092173]{position:fixed;right:1rem;bottom:calc(var(--app-footer-height, 48px) + 1rem + env(safe-area-inset-bottom));z-index:1060;background:#fff;border:1px solid rgba(33,37,41,.12);border-radius:.75rem;padding:.65rem;box-shadow:0 18px 45px #0f172a29,0 2px 8px #0f172a14;display:flex;align-items:center;gap:.65rem;width:min(25rem,calc(100vw - 2rem));color:#17202a}.reload-prompt__icon[data-v-bf092173]{display:inline-flex;align-items:center;justify-content:center;width:2rem;height:2rem;flex:0 0 2rem;border-radius:.6rem;background:#e9f3ff;color:#0f5fb8}.reload-prompt__copy[data-v-bf092173]{min-width:0;display:grid;gap:.05rem;flex:1 1 auto}.reload-prompt__title[data-v-bf092173]{font-size:.875rem;font-weight:700;line-height:1.2}.reload-prompt__text[data-v-bf092173]{font-size:.78rem;line-height:1.25;color:#52606d}.reload-prompt__actions[data-v-bf092173]{display:flex;align-items:center;gap:.25rem;flex:0 0 auto}.reload-prompt__dismiss[data-v-bf092173]{color:#52606d;text-decoration:none;padding-inline:.35rem}@media(max-width:575.98px){.reload-prompt[data-v-bf092173]{right:.75rem;bottom:calc(var(--app-footer-height, 48px) + .75rem + env(safe-area-inset-bottom));align-items:flex-start}.reload-prompt__actions[data-v-bf092173]{align-self:center;flex-direction:column}}:root{--medical-blue-50: #e3f2fd;--medical-blue-100: #bbdefb;--medical-blue-200: #90caf9;--medical-blue-300: #64b5f6;--medical-blue-400: #42a5f5;--medical-blue-500: #2196f3;--medical-blue-600: #1e88e5;--medical-blue-700: #0d47a1;--medical-blue-800: #1565c0;--medical-blue-900: #0d47a1;--medical-teal-50: #e0f2f1;--medical-teal-100: #b2dfdb;--medical-teal-200: #80cbc4;--medical-teal-300: #4db6ac;--medical-teal-400: #26a69a;--medical-teal-500: #009688;--medical-teal-600: #00897b;--medical-teal-700: #00796b;--status-success: #2e7d32;--status-success-bg: #e8f5e9;--status-warning: #f57c00;--status-warning-bg: #fff3e0;--status-danger: #c62828;--status-danger-bg: #ffebee;--status-info: #0277bd;--status-info-bg: #e1f5fe;--neutral-50: #fafafa;--neutral-100: #f5f5f5;--neutral-200: #eeeeee;--neutral-300: #e0e0e0;--neutral-400: #bdbdbd;--neutral-500: #9e9e9e;--neutral-600: #757575;--neutral-700: #616161;--neutral-800: #424242;--neutral-900: #212121;--border-subtle: #d9e0ea}:root{--shadow-none: none;--shadow-xs: 0 1px 2px 0 rgba(13, 71, 161, .05);--shadow-sm: 0 1px 3px 0 rgba(13, 71, 161, .1), 0 1px 2px 0 rgba(13, 71, 161, .06);--shadow-md: 0 4px 6px -1px rgba(13, 71, 161, .1), 0 2px 4px -1px rgba(13, 71, 161, .06);--shadow-lg: 0 10px 15px -3px rgba(13, 71, 161, .1), 0 4px 6px -2px rgba(13, 71, 161, .05);--shadow-xl: 0 20px 25px -5px rgba(13, 71, 161, .1), 0 10px 10px -5px rgba(13, 71, 161, .04);--shadow-2xl: 0 25px 50px -12px rgba(13, 71, 161, .25);--shadow-focus: 0 0 0 3px rgba(13, 71, 161, .25)}.shadow-none{box-shadow:var(--shadow-none)!important}.shadow-xs{box-shadow:var(--shadow-xs)!important}.shadow-sm{box-shadow:var(--shadow-sm)!important}.shadow-md{box-shadow:var(--shadow-md)!important}.shadow-lg{box-shadow:var(--shadow-lg)!important}.shadow-xl{box-shadow:var(--shadow-xl)!important}.shadow-2xl{box-shadow:var(--shadow-2xl)!important}.shadow-hover-sm:hover{box-shadow:var(--shadow-sm);transition:box-shadow var(--transition-base, .25s ease)}.shadow-hover-md:hover{box-shadow:var(--shadow-md);transition:box-shadow var(--transition-base, .25s ease)}.shadow-hover-lg:hover{box-shadow:var(--shadow-lg);transition:box-shadow var(--transition-base, .25s ease)}:root{--spacing-compact: .5rem;--spacing-base: .75rem;--spacing-comfortable: 1rem;--spacing-0: 0;--spacing-1: .25rem;--spacing-2: .5rem;--spacing-3: .75rem;--spacing-4: 1rem;--spacing-5: 1.5rem;--spacing-6: 2rem;--spacing-7: 2.5rem;--spacing-8: 3rem;--spacing-card-padding: var(--spacing-4);--spacing-form-group: var(--spacing-3);--spacing-table-cell: var(--spacing-2);--spacing-section: var(--spacing-6);--gap-compact: var(--spacing-2);--gap-base: var(--spacing-3);--gap-comfortable: var(--spacing-4)}.compact{--bs-gutter-y: var(--spacing-compact);--bs-gutter-x: var(--spacing-compact)}.spacing-base{--bs-gutter-y: var(--spacing-base);--bs-gutter-x: var(--spacing-base)}.spacing-comfortable{--bs-gutter-y: var(--spacing-comfortable);--bs-gutter-x: var(--spacing-comfortable)}.table-compact td,.table-compact th{padding:var(--spacing-table-cell)}.table-comfortable td,.table-comfortable th{padding:var(--spacing-4)}:root{--radius-none: 0;--radius-xs: .125rem;--radius-sm: .25rem;--radius-md: .375rem;--radius-lg: .5rem;--radius-xl: .75rem;--radius-2xl: 1rem;--radius-full: 9999px}.radius-none{border-radius:var(--radius-none)!important}.radius-xs{border-radius:var(--radius-xs)!important}.radius-sm{border-radius:var(--radius-sm)!important}.radius-md{border-radius:var(--radius-md)!important}.radius-lg{border-radius:var(--radius-lg)!important}.radius-xl{border-radius:var(--radius-xl)!important}.radius-2xl{border-radius:var(--radius-2xl)!important}.radius-full{border-radius:var(--radius-full)!important}:root{--font-family-sans: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, "Noto Sans", sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", "Noto Color Emoji";--font-family-mono: SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace;--font-weight-light: 300;--font-weight-normal: 400;--font-weight-medium: 500;--font-weight-semibold: 600;--font-weight-bold: 700;--font-size-xs: .75rem;--font-size-sm: .875rem;--font-size-base: 1rem;--font-size-lg: 1.125rem;--font-size-xl: 1.25rem;--font-size-2xl: 1.5rem;--font-size-3xl: 1.875rem;--font-size-4xl: 2.25rem;--line-height-tight: 1.25;--line-height-normal: 1.5;--line-height-relaxed: 1.75;--letter-spacing-tight: -.025em;--letter-spacing-normal: 0;--letter-spacing-wide: .025em}.font-mono{font-family:var(--font-family-mono)}.text-tight{line-height:var(--line-height-tight)}.text-relaxed{line-height:var(--line-height-relaxed)}.gene-name{font-family:var(--font-family-mono);font-style:italic;font-weight:var(--font-weight-medium)}.protein-name{font-family:var(--font-family-mono);font-weight:var(--font-weight-medium)}.scientific-data{font-family:var(--font-family-mono);font-size:var(--font-size-sm);letter-spacing:var(--letter-spacing-tight)}:root{--transition-fast: .15s cubic-bezier(.4, 0, .2, 1);--transition-base: .25s cubic-bezier(.4, 0, .2, 1);--transition-slow: .35s cubic-bezier(.4, 0, .2, 1);--transition-colors: background-color .25s, border-color .25s, color .25s;--transition-shadow: box-shadow .25s cubic-bezier(.4, 0, .2, 1);--transition-transform: transform .25s cubic-bezier(.4, 0, .2, 1);--focus-ring-width: .25rem;--focus-ring-color: rgba(13, 71, 161, .25);--focus-ring-offset: 2px}@media(prefers-reduced-motion:reduce){:root{--transition-fast: .01ms;--transition-base: .01ms;--transition-slow: .01ms;--transition-colors: none;--transition-shadow: none;--transition-transform: none}*,*:before,*:after{animation-duration:.01ms!important;animation-iteration-count:1!important;transition-duration:.01ms!important}}.focus-visible:focus-visible{outline:var(--focus-ring-width) solid var(--focus-ring-color);outline-offset:var(--focus-ring-offset);box-shadow:none}.focus-visible:focus:not(:focus-visible){outline:none}.sysndd-chip{display:inline-flex;align-items:center;padding:.15em .5em;font-size:.75rem;font-weight:500;line-height:1.4;white-space:nowrap;border-radius:var(--radius-full, 9999px);text-decoration:none;border:none;cursor:default;transition:background-color .15s ease-in-out,color 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#2e7d32)}.sysndd-chip--warning{background-color:var(--status-warning-bg, #fff3e0);color:#e65c00}.sysndd-chip--danger{background-color:var(--status-danger-bg, #ffebee);color:var(--status-danger, #c62828)}.sysndd-chip--info{background-color:var(--status-info-bg, #e1f5fe);color:#01579b}.sysndd-annotation--gene{border-radius:2px;padding:0 2px;cursor:help;background-color:var(--medical-blue-50, #e3f2fd);color:var(--medical-blue-700, #0d47a1)}.sysndd-annotation--disease{border-radius:2px;padding:0 2px;cursor:help;background-color:#ffe0b2;color:#bf360c}.sysndd-annotation--variant{border-radius:2px;padding:0 2px;cursor:help;background-color:#f8bbd9;color:#880e4f}.sysndd-annotation--species{border-radius:2px;padding:0 2px;cursor:help;background-color:#c8e6c9;color:#1b5e20}.sysndd-annotation--chemical{border-radius:2px;padding:0 2px;cursor:help;background-color:#e1bee7;color:#4a148c}.sysndd-annotation--match{border-radius:2px;padding:0 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